นโยบายงานวิจัย /จรรยาบรรณนักวิจัย /ระดับคุณภาพบทความวิจัยตีพิมพ์ /ระดับคุณภาพผลงานวิชาการ /แหล่งทุน /ดาวน์โหลด /ฐานข้อมูลวิจัย /วิเคราะห์-สังเคราะห์งานวิจัย /ลิขสิทธิ์ /ข่าว


Analysis of Potentilally Inapproproate Medication in elderly patients according to 2014 STOPP/START criteria


Author

-

Chaekhuntod N.1, Kewtanong W.1, Supapaan T.2, Samseethong T.3*

 


Journal

- The 10th Annual Northeast Pharmacy Research Conference of 2018 (NEPhReC 2018)

Volume

- 0

Year

- 2018

Publication type

-

Page list

- -

Abstract

   

 Introduction: Elderly population is increasing in Thailand. Multiple comorbidities, polypharmacy and prescription of potentially inappropriate medications (PIMs) could have profound effects on the elderly patients. PIMs in the elderly are common and are associated with adverse drug events (ADEs), serious drug-drug interaction and may contribute to excessive morbidity and mortality. The Screening Tool of Older Persons' potentially inappropriate Prescriptions/Screening Tool to Alert doctors to the Right Treatment criteria (STOPP/START) 2014 has been widely used to rationalize prescribing in hospital setting. This study aimed to determine the percentage and frequency of PIMs in the elderly outpatients at a Sunprasitthiprasong hospital using the 2014 STOPP/START criteria. Methods: The retrospective study was conducted by collecting data using the outpatient prescription database between 1st   January and 31st March 2016. Data were included from patients above 65 years of age with polypharmacy (five or more medications per prescription). PIMs was assessed using 2014 STOPP/ START criteria by two investigators. Results: Four hundred thirty-three patients were included in this study. The average age was 74.05 years. The majority of the patients were female (51.57%). Out of these patients, 56.90% had hypertension, 34.14% had dyslipidemia and 28.81% had diabetes mellitus. The average number of medicines prescribed per patient was 8.76. According to the criteria, 243 patients (58.83%) were prescribed at least 1 PIMs. The most frequent PIMs identified by using the STOPP criteria were benzodiazepines (22.31%) which increased the risk of fall in old patients, first generation antihistamines (13.53%) and regular opioids without concomitant laxative (10.78%). On the other hands, a few PIMS were identified by using START criteria. The most frequent PIMs for the START criteria was the chronic systemic glucocorticoid without bisphosphonate therapy. Conclusion: The study shows high prevalence of prescribing PIMs in elderly patients. Most commonly prescribed PIMS were benzodiazepines, antihistamine drugs and opioids.  Efforts to reduce PIMS in elderly patients should focus these drugs prescribing, duration of therapy and side effects. This results could help increase awareness to other healthcare settings as well.


Keywords

   

Elderly, Potentially Improper Medication, 2014 STOPP/START Criteria